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α-Hederin
Cat. No.:
OB0626WX-1391
Appearance:
Crystalline solid
Purity:
≥98%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
α-Hederin is a plant-derived triterpenoid saponin that demonstrates a diverse spectrum of biological and pharmacological activities. It modulates smooth muscle dynamics by stimulating spontaneous motoric activity in gastric tissues and exhibits potent cytotoxicity against multiple human and murine carcinoma cell lines while successfully prolonging survival markers in tumor models. Additionally, this bioactive compound displays anti-inflammatory and antinociceptive profiles, mitigates induced paw edema, and provides robust hepatoprotection by suppressing systemic transaminase elevations and downregulating specific hepatic cytochrome P450 isoforms.
Synonyms:
(3β,4α)-3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-olean-12-en-28-oic acid; Kalopanaxsaponin A; Koronaroside A; NSC 106553; Pulsatilla saponin A; Alpha-hederin; Rha-Ara-3beta-hederagenin; 27013-91-8
CAS No.:
27013-91-8
Compound CID:
73296
Formula:
C41H66O12
Formula Weight:
751
Specification
Source:
Lonicera fulvotomentosa
Solubility in DMSO:
10 mg/mL
Solubility in Ethanol:
5 mg/mL
Solubility in DMF:
10 mg/mL
Storage:
Storage at -20°C.
Applications:
α-Hederin operates as a specialized bioactive triterpenoid saponin reference standard utilized to investigate membrane permeabilization dynamics, modulate transmembrane receptor signaling channels, and profile selective tumor-cell cytotoxicity pathways within biochemical screening assays.
