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MCTR3
Cat. No.:
OB0626WX-2138
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
MCTR3 is a macrophage-derived specialized pro-resolving mediator biosynthesized from docosahexaenoic acid through a coordinated enzymatic cascade involving maresin 1, MCTR1, and MCTR2 intermediates. This bioactive sulfidoconjugated lipid mediator functions as a master regulator of host immune responses, driving tissue regeneration, blocking pathogenic neutrophil infiltration, accelerating the resolution phase of acute peritonitis, and downregulating pro-inflammatory eicosanoids while actively augmenting macrophage phagocytosis.
Synonyms:
13R-[[(2R)-2-amino-2-carboxyethyl]thio]-14S-hydroxy-4Z,7Z,9E,11E,16Z,19Z-docosahexaenoic acid; 13-cysteinyl-14-hydroxy-Docosahexaenoic Acid; (4Z,7Z,9E,11E,13R,14S,16Z,19Z)-13-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-14-hydroxydocosa-4,7,9,11,16,19-hexaenoic acid; (13R)-S-cysteinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoic acid; (4Z,7Z,9E,11E,13R,14S,16Z,19Z)-13-[(2R)-2-amino-2-carboxyethyl]sulfanyl-14-hydroxydocosa-4,7,9,11,16,19-hexaenoic acid; 13-cysteinyl-maresin 2; Maresin Conjugates in Tissue Regeneration 3; Maresin Sulfido Conjugate 3; 1784701-63-8
CAS No.:
1784701-63-8
Compound CID:
122368873
Formula:
C25H37NO5S
Formula Weight:
463.6
Specification
λmax:
282 nm
Solubility in DMSO:
50 mg/mL
Solubility in Ethanol:
1 mg/mL
Solubility in DMF:
50 mg/mL
Solubility in Other Solvents:
Ethanol:H20 mixture: 2 mg/mL; PBS: 0.1 mg/mL
Storage:
Storage at -80°C.
Applications:
MCTR3 serves as a specialized pro-resolving mediator reference compound and supports lipid mediator profiling, LC-MS/MS method development, and analytical characterization of macrophage-derived mediator pathways.
