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Vitamin B12 test kit

HADH Blocking Peptide (C-YERGDASKEDID)

Cat. No.: OB0526-WX31
Origin: Synthetic
Conjugation: Unconjugate
Species Reactivity: Human; Mouse; Rat; Dog
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Product Overview

Description: HADH Blocking Peptide (C-YERGDASKEDID) is an epitope-matched synthetic peptide corresponding to a specific region of the HADH protein. It is intended for antibody blocking experiments where confirmation of antibody specificity is required. This peptide serves as an effective negative control for evaluating HADH immunoreactivity and assay reliability.
Sequence: C-YERGDASKEDID
Molecular Weight: 1512.5 Da
Purity: ≥95%
Applications: Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay

Specification

Storage: Storage at -20°C.
Shipping Condition: Shipped with ice packs.
Handling Notes: During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.

Target Profile

Full Name: Hydroxyacyl-CoA Dehydrogenase
Alternative Names: HADH; Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; HAD; HAD1; HADHSC; SCHAD
Summary: Hydroxyacyl-CoA dehydrogenase (HADH) is a mitochondrial enzyme located in the matrix, where it catalyzes the oxidation of straight-chain 3-hydroxyacyl-CoA intermediates during fatty acid beta-oxidation. Its enzymatic activity is particularly high toward medium-chain fatty acid substrates. HADH is involved in mitochondrial energy metabolism, and mutations in the gene can cause a form of familial hyperinsulinemic hypoglycemia. A related pseudogene has also been identified on human chromosome 15.
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