GRP78 Blocking Peptide (C-ESHQDADIEDFK)

Cat. No.: OB0526-WX50

Origin: Synthetic

Conjugation: Unconjugate

Species Reactivity: Human

Size:

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Product Overview

Description: GRP78 Blocking Peptide (C-ESHQDADIEDFK) is a sequence-specific synthetic peptide corresponding to a distinct antigenic region of the GRP78 protein. It is designed to neutralize compatible anti-GRP78 antibodies through competitive inhibition, providing a reliable negative control for immunoblotting and immunostaining procedures.

Sequence: C-ESHQDADIEDFK

Molecular Weight: 1566.6 Da

Purity: ≥95%

Applications: Western blotting; ELISA; IHC; IF; Functional Assay; Cell Culture; Binding Assay

Specification

Storage: Storage at -20°C.

Shipping Condition: Shipped with ice packs.

Handling Notes: During shipping, trace amounts of the blocking peptide may adhere to the interior surface of the vial cap. Before opening, it is highly recommended to briefly centrifuge the vial to bring all contents to the bottom.

Target Profile

Full Name: Heat Shock Protein Family A (Hsp70) Member 5

Alternative Names: HSPA5; Glucose-Regulated Protein, 78kDa; Prev. Symbol: GRP78; HSP70 Family Protein 5; BiP; Heat Shock 70kD Protein 5 (Glucose-Regulated Protein, 78kD); Immunoglobulin Heavy Chain-Binding Protein; Endoplasmic Reticulum Lumenal Ca(2+)-Binding Protein Grp78; Heat Shock Protein 70 Family Protein 5; Epididymis Secretory Sperm Binding Protein Li 89n; Heat Shock Protein Family A Member 5; Endoplasmic Reticulum Chaperone BIP; Endoplasmic Reticulum Chaperone BiP; HEL-S-89n; 78 KDa Glucose-Regulated Protein; GRP-78; Binding-Immunoglobulin Protein

Gene ID: 3309

Uniprot ID: P11021

Summary: HSPA5, also known as BiP or GRP78, is a molecular chaperone located primarily in the endoplasmic reticulum. It assists with protein folding, protein quality control, and the maintenance of endoplasmic reticulum function. HSPA5 also participates in the cellular response to endoplasmic reticulum stress and is studied in research on proteostasis, metabolic dysfunction, and cellular stress signaling.

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