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Glycolithocholic acid, sodium salt
Cat. No.:
OB0626WX-2323
Appearance:
Crystalline solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, IR, and HPLC.
Size:
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Product Overview
Description:
Glycolithocholic acid is a glycine-conjugated secondary bile acid produced via the downstream microbial metabolism of lithocholic acid. This hydrophobic sterol conjugate undergoes significant accumulation in liver tissue following specific bile acid therapies, modulates systemic plasma levels in response to peptide hormone stimulation, and exhibits a distinct concentration trajectory across different developmental age brackets.
Synonyms:
N-[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]-glycine, monosodium salt; GLCA Lithocholylglycine; 24404-83-9; Glycolithocholic acid sodium salt; Glycolithocholic acid (sodium); Sodium Glycolithocholate; N-(3alpha-Hydroxy-5beta-cholan-24-oyl)glycine Sodium Salt; N-[(3alpha,5beta)-3-Hydroxy-24-oxocholan-24-yl]glycine Sodium Salt; Lithocholylglycine (sodium)
CAS No.:
24404-83-9
Compound CID:
23707120
Formula:
C26H42NO4 • Na
Formula Weight:
455.6
Specification
Solubility in DMSO:
20 mg/mL
Solubility in Ethanol:
12 mg/mL
Solubility in Other Solvents:
DMSO:PBS mixture: 0.2 mg/mL
Storage:
Storage at -20°C.
Applications:
Glycolithocholic acid, sodium salt serves as a reference compound for bile acid metabolomics and analysis of glycine-conjugated secondary bile acids. It supports targeted LC-MS/MS profiling, investigations of bile acid metabolism, microbial biotransformation, and characterization of enterohepatic bile acid circulation.
