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7α-Thiomethylspironolactone
Cat. No.:
OB0626WX-757
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
7α-Thiomethylspironolactone is a sulfur-containing steroidal derivative arising natively within mammalian metabolic systems as a primary, downstream metabolite generated from the intensive systemic biotransformation of the synthetic antimineralocorticoid drug spironolactone.
Synonyms:
(7α,17α)-17-hydroxy-7-(methylthio)-3-oxo-pregn-4-ene-21-carboxylic acid, γ-lactone; SC 26519; 7alpha-Thiomethylspironolactone; 7-Thiomethylspirolactone; 7alpha-(Thiomethyl)spironolactone; 7-alpha-Thiomethyl Spironolactone; 7|A-(Thiomethyl)spironolactone; (7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-7-methylsulfanylspiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione; 7a-Thiomethyl Spironolactone; 7alpha-Thiomethylspirolactone; 7alpha-Thiomethyl-SL; 7a-Thiomethylspironolactone; (7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-7-methylsulfanyl-spiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,5'-tetrahydrofuran]-2',3-dione; 7|A-Thiomethylspironolactone; 7-(Thiomethyl)spironolactone; (1R,3aS,3bR,4R,9aR,9bS,11aS)-9a,11a-Dimethyl-4-(methylsulfanyl)-2,3,3a,4,5,8,9,9a,9b,10,11,11a-dodecahydrospiro[cyclopenta[a]phenanthrene-1,2'-oxolane]-5',7(3bH)-dione; (2'R,7R,8R,9S,10R,13S,14S)-10,13-dimethyl-7-(methylthio)-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione; 10,13-Dimethyl-7-(methylsulfanyl)-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydrospiro[cyclopenta[a]phenanthrene-17,2'-oxolane]-3,5'(2H)-dione; Pregn-4-ene-21-carboxylic acid, 17-hydroxy-7-(methylthio)-3-oxo-, gamma-lactone, (7alpha,17alpha)-; 38753-77-4
CAS No.:
38753-77-4
Compound CID:
162325
Formula:
C23H32O3S
Formula Weight:
388.6
Specification
Storage:
Storage at -20°C.
Applications:
7α-Thiomethylspironolactone acts as a sulfur-functionalized steroidal metabolite standard to optimize complex multi-component quantitative separation matrices and trace alternative steroid transformation cascades without endogenous baseline overlap.
