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Glipizide
Cat. No.:
0225LY-0790
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
Glipizide is a second-generation, short-acting sulfonylurea utilized for its hypoglycemic activity.
Synonym:
29094-61-9; Glydiazinamide; Glibenese; Melizide; Aldiab; Ozidia; N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-5-methylpyrazine-2-carboxamide; Pyrazinecarboxamide, N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-5-methyl-; N-(4-(beta-(5-Methylpyrazine-2-carboxamido)ethyl)benzenesulphonyl)-N'-cyclohexylurea; Urea, 1-cyclohexyl-3-((p-(2-(5-methylpyrazinecarboxamido)ethyl)phenyl)sulfonyl)-; N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide
CAS No.:
29094-61-9
Compound CID:
3478
Formula:
C21H27N5O4S
Formula Weight:
445.54
Specification
Targets&IC50:
KATP: 6.4 nM ATP-sensitive potassium (IC50)
Relative Density:
1.34 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Glipizide can be used in diabetes research to study the stimulation of insulin secretion through the closure of ATP-sensitive potassium channels.
Library Information
Target:
ABC; Potassium channel; PPAR
Receptor:
ABCC; Potassium channel; PPARγ
Pathways:
Membrane transporter/Ion channel; Metabolism; DNA damage/DNA repair
Plate Number:
AOCL-11
Plate Location:
b9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
82 mg/mL; 184.05 mM
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)





