FR 180204

Cat. No.: OB0225WX-2362

Appearance: Solid

Purity: ≥99%

Identity: Confirmed by NMR, HPLC, and LC-MS.

Size:

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Product Overview

Description: FR 180204 is a potent, ATP-competitive inhibitor characterized by its high selectivity for the ERK1 and ERK2 kinase isoforms.

Synonym: FR180204; 865362-74-9; FR-180204; ERK inhibitor II; 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-2H-pyrazolo[3,4-c]pyridazin-3-amine; 1H-Pyrazolo(3,4-C)pyridazin-3-amine, 5-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-; 5-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)-2H-pyrazolo(3,4-C)pyridazin-3-amine; 5-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-1H-pyrazolo[3,4-c]pyridazin-3-amine; 5-{2-phenylpyrazolo[1,5-a]pyridin-3-yl}-2H-pyrazolo[3,4-c]pyridazin-3-amine; MFCD14585805; 3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-7H-pyrazolo[3,4-c]pyridazin-5-amine; 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3 -ylamine; 5-(2-phenylH-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine

CAS No.: 865362-74-9

Compound CID: 11493598

Formula: C₁₈H₁₃N₇

Formula Weight: 327.34

Specification

Targets&IC50: ERK1: 0.31 μM(Ki); ERK2: 0.14 μM(Ki)

Relative Density: 1.55 g/cm³

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: FR 180204 is used in neuropharmacology and inflammation research as a selective, ATP-competitive ERK1/2 inhibitor to investigate the role of MAPK signaling in nociception and inflammatory responses.