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DSPE-mPEG550, sodium salt
Cat. No.:
OB0626WX-580
Appearance:
Solid
Purity:
≥90%
Identity:
Confirmed by NMR, TLC, and IR.
Size:
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Product Overview
Description:
DSPE-mPEG550 is a highly specialized, structurally uniform PEGylated phospholipid conjugate synthesized by covalently attaching a discrete methoxy-polyethylene glycol chain with an average molecular weight of 550 Daltons to the terminal headgroup of 1,2-distearoyl-rac-glycero-3-phosphoethanolamine, engineered as a premier stealth lipid component to optimize surface hydration, prevent opsonization, and prolong systemic circulation kinetics in advanced liposomal and lipid nanoparticle (LNP) drug delivery architectures.
Conjugation:
PEGylated
Synonyms:
α-[6-hydroxy-6-oxido-1,12-dioxo-9-[(1-oxooctadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphanonacos-1-yl]-ω-methoxy-poly(oxy-1,2-ethanediyl), sodium salt; 1,2-Dioctadecanoyl-sn-glycero-3-Phosphoethanolamine-N-mPEG(550); 1,2-Distearoyl Phosphatidylethanolamine-N-mPEG(550); 1,2-Distearoyl-sn-glycero-3-Phosphoethanolamine-N-methoxy-Polyethylene Glycol-550; 1,2-DSPE-mPEG(550); PE(18:0/18:0)-mPEG(550); PtdEtn-(1,2-Distearoyl)-N-mPEG(550)
Formula:
(C2H4O)nC43H84NO10P • XNa
Specification
Solubility in Other Solvents:
Chloroform: 10 mg/mL
Storage:
Storage at -20°C.
Applications:
DSPE-mPEG550, sodium salt acts as an advanced PEGylated phospholipid matrix component designed for optimizing the surface hydrophilic shielding, structural lateral stability parameters, and outer shell diffusion kinetics of engineered lipid nanoparticle delivery architectures.