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DMT7
Cat. No.:
OB0626WX-3690
Appearance:
Liquid
Purity:
≥90%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
DMT7 is a specialized ionizable cationic lipid possessing an apparent pKa of 6.5, engineered as a core structural element for therapeutic lipid nanoparticles. This ionizable architecture facilitates the co-encapsulation of multiple therapeutic agents, optimizing intracellular release to modulate the tumor microenvironment. Formulations leveraging this lipid matrix shift the immunological profile within targeted tissues by decreasing regulatory T cell populations, promoting the polarization of tumor-associated M1 macrophages, and triggering a robust local release of pro-inflammatory cytokines and interferons to suppress tumor volume and metastatic growth.
Synonyms:
1-(2-(dimethylamino)ethyl)-3-((6Z,9Z,28Z,31Z)-heptatriaconta-6,9,28,31-tetraen-19-yl)thiourea; 3080542-12-4
CAS No.:
3080542-12-4
Compound CID:
172677099
Formula:
C42H79N3S
Formula Weight:
658.2
Specification
Solubility in DMSO:
1-10 mg/mL
Solubility in Ethanol:
≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
DMT7 supports lipid nanoparticle and delivery system research as a functional lipid component. It can be utilized for investigating lipid composition, nanoparticle formulation strategies, and the relationship between lipid structure and delivery-related properties.
