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Cho-es-Lys
Cat. No.:
OB0626WX-3883
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by IR, TLC, and HPLC.
Size:
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Product Overview
Description:
Cho-es-Lys is a cationic cholesterol derivative featuring a rigid sterol core covalently linked to an L-lysine head group containing two distinct primary amines via a flexible hexanediol spacer. This amphiphilic molecular layout presents defined pKa parameters to coordinate polyanionic nucleic acid backbones, promoting efficient cellular uptake, transmembrane delivery, and the targeted downregulation of intracellular transcription products.
Synonyms:
L-lysine, 6-[[[(3β)-cholest-5-en-3-yloxy]carbonyl]oxy]hexyl ester, 2,2,2-trifluoroacetate; CEL; 1356250-80-0
CAS No.:
1356250-80-0
Compound CID:
171042901
Formula:
C40H72N2O5 • 2CF3COO
Formula Weight:
887.1
Specification
Solubility in Other Solvents:
Ethanol: 2 mg/mL
Storage:
Storage at -20°C.
Applications:
Cho-es-Lys serves as a cholesterol-derived lipid conjugate for membrane engineering and functional lipid assembly research. It supports lipid conjugation strategies, nanoparticle formulation, membrane interaction studies, and development of cholesterol-functionalized delivery systems.