Products
Online Inquiry
CF3-2N6-UC18
Cat. No.:
OB0626WX-3627
Appearance:
Oil
Purity:
≥90%
Identity:
Confirmed by NMR and HPLC.
Size:
Add to basket
Product Overview
Description:
CF3-2N6-UC18 is an ionizable cationic lipid derivative incorporating a chloroquine-based core structure to enhance endosomal escape. The chloroquine-derived moiety promotes cellular internalization via micropinocytosis pathways and accelerates lipid bilayer disruption following endosomal acidification. When administered systemically, lipid assemblies incorporating this molecule show a strong preference for localized accumulation within regional lymphoid structures.
Synonyms:
N1,N1-di-9-octadecen-1-yl-N6-[7-(trifluoromethyl)-4-quinolinyl]-1,6-hexanediamine; CF3-2N6-UC18 Lipid; 3042854-95-2
CAS No.:
3042854-95-2
Compound CID:
178325058
Formula:
C52H88F3N3
Formula Weight:
812.3
Specification
Solubility in Ethanol:
≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
CF3-2N6-UC18 is utilized as a specialized ionizable lipid reagent for lipid nanoparticle formulation research. It supports characterization of lipid materials, investigation of nanoparticle composition, and evaluation of delivery system properties.