Bioymifi

Cat. No.: OB0225WX-2719

Appearance: Solid

Purity: ≥98%

Identity: Confirmed by NMR, and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Bioymifi is a small-molecule agonist of death receptor 5 (DR5) that binds the extracellular domain with a Kd of 1.2 micromolar, leading to DR5 clustering and the induction of apoptosis.

Synonym: 1420071-30-2; (Z)-5-(5-((3-(4-Bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 5-[5-[[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-; Bioymifi (~90%); 5-[5-[(Z)-[3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]isoindole-1,3-dione; DR5 Activator; (Z)-5-(5-[(3-[4-Bromophenyl]-2-imino-4-oxothiazolidin-5-ylidene)methyl]furan-2-yl)isoindoline-1,3-dione; 5-(5-{[(5Z)-3-(4-bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-2,3-dihydro-1H-isoindole-1,3-dione; 5-(5-{[3-(4-Bromophenyl)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}-2-furyl)-1H-isoindole-1,3(2H)-dione; 5-[5-[[(5Z)-3-(4-Bromophenyl)-2-imino-4-oxo-5-thiazolidinylidene]methyl]-2-furanyl]-1H-isoindole-1,3(2H)-dione; (Z)-5-(5-((3-(4-Bromophenyl)-2-imino-4-oxothiazolidin-5-ylidene)methyl)furan-2-yl)isoindoline-1,3-dione; MFCD28118988

CAS No.: 1420071-30-2

Compound CID: 70678419

Formula: C₂₂H₁₂BrN₃O₄S

Formula Weight: 494.32

Specification

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Bioymifi is utilized in oncology research as a small molecule Smac mimetic to study the sensitization of tumor cells to TRAIL-induced apoptosis by antagonizing Inhibitor of Apoptosis Proteins (IAPs).