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Azide-Polysarcosine150
Cat. No.:
OB0626WX-3758
Appearance:
Solid
Purity:
≥90%
Identity:
Confirmed by NMR, TLC, and IR.
Size:
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Product Overview
Description:
Azide-Polysarcosine150 is a functionalized, azide-terminated hydrophilic polypeptoid polymer derived from an amine-terminated polysarcosine core architecture. This specialized polymer block acts as a non-peptidic, hydrophobicity-masking shield when conjugated to antibody architectures, optimizing the structural stability and pharmacokinetics of antibody-drug conjugates to facilitate the site-specific, tumor-selective cleavage and release of cytotoxic payloads.
Conjugation:
Azide-functionalized
Synonyms:
N-(3-azidopropyl)-2-(methyl((methylamino)methyl)amino)acetamide; Azide-pSar150; N3-pSar150; N3-Polysarcosine150
Formula:
(C3H5NO)nC5H13N5
Specification
Solubility in Other Solvents:
Soluble in chloroform.
Storage:
Storage at -20°C.
Applications:
Azide-Polysarcosine150 serves as a functional polymer-lipid modification reagent for developing azide-containing lipid-based materials and bioconjugation strategies. It supports studies involving surface functionalization, click chemistry-based modification approaches, and characterization of polymer-modified delivery systems.
