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Lipid N2-3L
Cat. No.:
OB0626WX-3717
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
Lipid N2-3L is a highly basic ionizable crystalline lipid displaying a pKa of 8.99, developed for the assembly of supramolecular lipid nanoparticles. This unique structural architecture promotes particle retention at localized sites and coordinates transport to draining lymphoid networks. When co-formulated with adjuvant molecules, the lipid matrix drives dendritic cell maturation and enhanced antigen presentation, triggering potent immune cascades that suppress tumor growth and extend survival profiles.
Synonyms:
9Z-octadecenoic acid, 3-[2-[(2-hexyl-1-oxodecyl)oxy]ethyl]-14-hydroxy-12-(2-hydroxyethyl)-7-oxo-6-oxa-3,8,12-triazatetradec-1-yl ester; 3-(2-((2-hexyldecanoyl)oxy)ethyl)-14-hydroxy-12-(2-hydroxyethyl)-7-oxo-6-oxa-3,8,12-triazatetradecyl oleate; 2924606-55-1
CAS No.:
2924606-55-1
Compound CID:
172677391
Formula:
C48H93N3O8
Formula Weight:
840.3
Specification
Solubility in DMSO:
≥10 mg/mL
Solubility in Ethanol:
≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
Lipid N2-3L supports lipid nanoparticle research by providing a specialized lipid material for formulation studies. It can be used to investigate lipid assembly behavior, nanoparticle engineering, and the relationship between lipid structure and delivery-related properties.