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AS601245
Cat. No.:
0225LY-1064
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and HPLC.
Size:
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Product Overview
Description:
AS601245 functions as a JNK inhibitor that offers neuroprotective qualities.
Synonym:
345987-15-7; AS-601245; 1,3-benzothiazol-2-yl(2-((2-(3-pyridinyl)ethyl)amino)-4-pyrimidinyl)acetonitrile; 2-(1,3-benzothiazol-2-yl)-2-[2-(2-pyridin-3-ylethylamino)pyrimidin-4-yl]acetonitrile; 2-(benzo[d]thiazol-2-yl)-2-(2-((2-(pyridin-3-yl)ethyl)amino)pyrimidin-4-yl)acetonitrile; (2s)-1,3-Benzothiazol-2-Yl{2-[(2-Pyridin-3-Ylethyl)amino]pyrimidin-4-Yl}ethanenitrile; AS 601245
CAS No.:
345987-15-7
Compound CID:
10109823
Formula:
C20H16N6S
Formula Weight:
372.45
Specification
Targets&IC50:
JNK3 (human): 70 nM; JNK1 (human): 150nM; JNK2 (human): 220nM
Relative Density:
1.366 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
AS601245 can be used in neuropharmacology to investigate the neuroprotective effects of JNK inhibition in cerebral ischemia models.
Library Information
Target:
JNK
Receptor:
hJNK1; hJNK2; hJNK3
Pathways:
MAPK signaling; Inflammation; Apoptosis
Plate Number:
AOCL-14
Plate Location:
f9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
50 mg/mL; 134.25 mM
