Product Overview
Description:
AdipoUpX™ Human OTOP1 MSCV Particle (Overexpression) enables stable overexpression of the human OTOP1 gene, encoding a proton-selective ion channel involved in cellular pH regulation. OTOP1 has been associated with vestibular function and emerging links to energy balance and adipocyte biology. The MSCV retroviral vector ensures durable gene expression in stem cells and additional mammalian systems. Each batch is released only after validated titer, sterility, and mycoplasma testing.
Production Cell Line:
HEK293T
Promoter:
Ubi; CMV; EF1a; Others
Product Availability:
Produced Upon Order
Specification
Titer Test:
qPCR
Insert Verification:
Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.
Sterility Test:
No microbial contamination was detected in any product.
Mycoplasma Test:
No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.
Other QC:
Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.
Storage:
The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.
Stability:
Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.
Shipping Condition:
Our MSCV retroviral products are shipped using dry ice.
Handling Notes:
Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.
Intended Use:
This product is intended for research use only and is not for use in diagnosis or therapeutic applications.
Product Disclaimer:
Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.
Target Profile
Gene Name:
OTOP1
Full Name:
Otopetrin 1
Summary:
OTOP1 encodes an otopetrin family transmembrane protein involved in calcium signaling. In addition to its role in vestibular function, OTOP1 expression is induced in white adipose tissue during obesity. The protein participates in anti-inflammatory pathways that counteract obesity-induced adipose inflammation and support metabolic homeostasis.
