AdipoUpX™ Human CNR1 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human CNR1 MSCV Particle (Overexpression) is a stable integration tool for the specific and efficient overexpression of the human CNR1 (CB1 receptor) gene. The cannabinoid receptor 1 is a major regulator of appetite and peripheral lipid metabolism. Its MSCV structure is optimized for stem cells and various mammalian lineages, ensuring robust integration for GPCR signaling studies in stable cell models. Every batch undergoes comprehensive quality control, including titer and mycoplasma testing, ensuring the repeatability of results.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: CNR1

Full Name: Cannabinoid receptor 1

Gene Symbol: CB1; CNR; CB-R; CB1A; CB1R; CANN6; CB1K5

Gene ID: 1268

RefSeq ID-1: NP_001153698.1

RefSeq ID-2: NM_001160226.3

Summary: CNR1 encodes cannabinoid receptor 1 (CB1), a G protein-coupled receptor that mediates the effects of cannabinoids, including Δ9-tetrahydrocannabinol. CB1 signaling modulates appetite, energy balance, and central nervous system function by inhibiting adenylate cyclase and regulating neuronal activity. Multiple transcript variants produce two distinct protein isoforms.

AdipoUpX™ Human CNR1 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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