AdipoUpX™ Human APOA5 MSCV Particle (Overexpression)

Product Overview

Description: AdipoUpX™ Human APOA5 MSCV Particle (Overexpression) is a professionally engineered vector particle providing efficient and stable overexpression of human APOA5. This apolipoprotein is a potent regulator of plasma triglyceride levels and lipid metabolism. The MSCV vector is optimized specifically for stem cells, hematopoietic stem cells, etc., making it an ideal choice for investigating hyperlipidemia in cellular models. This product supports flexible reporter gene customization and passes through exhaustive quality control screening to ensure experimental safety.

Production Cell Line: HEK293T

Promoter: Ubi; CMV; EF1a; Others

Product Availability: Produced Upon Order

Specification

Titer Test: qPCR

Insert Verification: Final QC confirmed the correct molecular size and integrity of the insert through specific PCR amplification.

Sterility Test: No microbial contamination was detected in any product.

Mycoplasma Test: No mycoplasma presence was detected in this final viral preparation upon comprehensive testing.

Other QC: Our service scope includes both customized supplementary testing and comprehensive in vitro/in vivo transduction assessments.

Storage: The necessity of immediate transfer to -80 °C storage following receipt is crucial for upholding the product's integrity.

Stability: Biological activity remains intact for 6-12 months when stored at -80°C. Once removed from the freezer, the diluted working material is stable for up to 2-3 weeks at 4°C.

Shipping Condition: Our MSCV retroviral products are shipped using dry ice.

Handling Notes: Store the vector according to specified conditions and aliquot it immediately upon receipt into low-protein-binding tubes, which is necessary to maintain titer because viral particles are highly sensitive to both temperature fluctuations and freeze-thaw cycles.

Intended Use: This product is intended for research use only and is not for use in diagnosis or therapeutic applications.

Product Disclaimer: Throughout all operational processes, users bear ultimate responsibility for product storage, handling, and compliance with all safety protocols, laws, regulations, and biosafety requirements. Although our company commits to product quality via rigorous internal QC inspections, the complexity of experimental conditions means we cannot guarantee product performance or experimental results in any specific application.

Target Profile

Gene Name: APOA5

Full Name: Apolipoprotein A5

Gene Symbol: RAP3; APOAV

Gene ID: 116519

RefSeq ID-1: NP_001160070.1

RefSeq ID-2: NM_001166598.2

Summary: APOA5 encodes an apolipoprotein involved in the regulation of plasma triglyceride levels, a critical risk factor for coronary artery disease. It is a component of HDL particles, and mutations can cause hypertriglyceridemia and type 5 hyperlipoproteinemia. Dysregulation of APOA5 affects lipid metabolism and contributes to obesity-related cardiovascular risk.

AdipoUpX™ Human APOA5 MSCV Particle (Overexpression)

Product Overview

Specification

Target Profile

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