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7-Ketositosterol
Cat. No.:
OB0626WX-501
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
7-Ketositosterol is a specialized phytosterol oxidation product (POP) generated via the intense thermal oxidation and degradation of the plant sterol sitosterol. This bioactive oxysterol compound exhibits targeted antineoplastic efficacy, successfully arresting the growth and restricting the survival of HL-60 acute myeloid leukemia (AML) cell lines with a measured IC50 value of 45.6 µM.
Synonyms:
3β-hydroxy-stigmast-5-en-7-one; 7-oxo-β-Sitosterol; 7-Oxositosterol; 3-Hydroxystigmast-5-en-7-one; (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one; (3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta(a)phenanthren-7-one; 7-oxo-beta-sitosterol; 3beta-hydroxystigmast-5-en-7-one; Stigmast-5-en-7-one, 3-hydroxy-, (3beta)-; stigmast-5-ene-3beta-ol-7-one; Stigmast-5-en-3.beta.-ol-7-one; Stigmast-5-en-7-one, 3-hydroxy-, (3|A)-; Stigmast-5-en-7-one, 3-hydroxy-, (3.beta.)-; (3S,8S,9S,10R,13R,14S,17R)-17-[(1R,4R)-4-Ethyl-1,5-dimethyl-hexyl]-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one; 7-Oxysitosterol; 7-keto-Sitosterol; Stigmast-5-en-3-ol-7-one; 2034-74-4
CAS No.:
2034-74-4
Compound CID:
160608
Formula:
C29H48O2
Formula Weight:
428.7
Specification
Source:
Synthetic
λmax:
238 nm
Solubility in Ethanol:
3 mg/mL
Solubility in DMF:
12 mg/mL
Storage:
Storage at -20°C.
Applications:
7-Ketositosterol acts as an oxo-functionalized phytosterol oxidation derivative reference standard for profiling secondary plant sterol breakdown paths, investigating sterol-induced membrane domain alterations, and optimizing analytical resolution indices.