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Tropolone
Cat. No.:
OB0626WX-1123
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, IR, and GC.
Size:
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Product Overview
Description:
Tropolone is a unique non-benzenoid aromatic terpene isolated from cupressaceous tree bark that features an expansive matrix of biological actions. It acts as a clear competitive inhibitor of catechol O-methyltransferase, possesses broad-spectrum bacteriostatic properties against diverse Gram-positive and Gram-negative bacterial panels, and exerts direct bactericidal clearance against Aeromonas hydrophila and Chromobacterium violaceum. Furthermore, this molecule limits acute inflammatory pathways by blocking lipopolysaccharide-driven nitric oxide generation in macrophages and modulates endocrine functions by decreasing thyroid radioiodide uptake in translational metabolic tracking.
Synonyms:
2-hydroxy-2,4,6-cycloheptatrien-1-one; 2-Hydroxytropone; α-Tropolone; NSC 89303; Purpurocatechol; 533-75-5
CAS No.:
533-75-5
Compound CID:
10789
Formula:
C7H6O2
Formula Weight:
122.1
Specification
Source:
Synthetic
λmax:
227 nm; 319 nm; 352 nm
Solubility in DMSO:
10 mg/mL
Solubility in Ethanol:
30 mg/mL
Solubility in DMF:
5 mg/mL
Solubility in Other Solvents:
Ethanol:PBS mixture: 0.14 mg/mL
Storage:
Storage at -20°C.
Applications:
Tropolone operates as an isolated seven-membered aromatic ring model compound for calibrating high-performance liquid chromatography retention systems, profiling non-canonical metal-chelating networks, and studying the biophysical interactions of small functionalized rings within synthetic lipid monolayers.
