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5α-hydroxy-6-keto Cholesterol
Cat. No.:
OB0626WX-3048
Appearance:
Crystalline solid
Purity:
≥98%
Identity:
Confirmed by TLC and HPLC.
Size:
Add to basket
Product Overview
Description:
5α-hydroxy-6-keto Cholesterol is an oxygenated sterol metabolite generated via sequential cholesterol-5,6-epoxide hydrolase and hydroxysteroid dehydrogenase processing. This potent oxysterol operates as a metabolic signaling molecule, altering endogenous cholesterol synthesis pathways and driving accelerated cellular proliferation and tumor volume expansion in receptor-dependent mouse xenograft models.
Synonyms:
3β,5α-dihydroxy-cholestan-6-one; 6-Oxo-3,5-diol Cholestane-6-oxo-3β,5α-diol; OCDO; Oncosterone; cholestan-6-oxo-3,5-diol; cholestan-6-oxo-3beta,5alpha-diol; Yakkasterone; 5|A-hydroxy-6-keto Cholesterol; 5alpha-hydroxy-6-keto Cholesterol; 3,5-Dihydroxycholestan-6-one; YS 64; YS-64; 3.beta.,5.alpha.-Dihydroxycholestan-6-one; 3beta,5alpha-Dihydroxycholestan-6-one; 3beta,5-Dihydroxy-5alpha-cholestan-6-one; 5-Hydroxy-6-keto cholesterol; 3beta,5-dihydroxy-5a-cholestan-6-one; 13027-33-3
CAS No.:
13027-33-3
Compound CID:
159461
Formula:
C27H46O3
Formula Weight:
418.7
Specification
Solubility in DMSO:
0.5 mg/mL
Solubility in Ethanol:
5 mg/mL
Solubility in DMF:
20 mg/mL
Storage:
Storage at -20°C.
Applications:
5α-hydroxy-6-keto Cholesterol serves as a reference compound for oxidized cholesterol analysis and sterol metabolite characterization. It supports lipidomic profiling, structural identification, and investigation of cholesterol oxidation-related lipid species.
