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Phorbol
Cat. No.:
OB0626WX-2017
Appearance:
Crystalline solid
Purity:
≥98%
Identity:
Confirmed by NMR, TLC, UV, and HPLC.
Size:
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Product Overview
Description:
Phorbol is a natural tetracyclic diterpene core scaffold originally derived from the oil matrices of Croton tiglium. Characterized by its specialized rigid polycyclic framework, this non-promoting diterpenoid serves as an invaluable, high-purity starting material for the semisynthesis of diverse phorbol diesters engineered to map protein kinase C isotype activation via C1 domain association.
Synonyms:
(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b,9,9a-tetrahydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5H-cyclopropa[3,4]benz[1,2-e]azulen-5-one; (+)-Phorbol; 4-beta-Phorbol; 4beta-Phorbol; 4,9,12-beta,13,20-Pentahydroxy-1,6-tigliadien-3-on; 4,9,12beta,13,20-pentahydroxy-1,6-tigliadien-3-one; 4,9,12beta,13,20-pentahydroxytiglia-1,6-dien-3-one; (1S,2S,6R,10S,11R,13S,14R,15R)-1,6,13,14-tetrahydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyltetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dien-5-one; 4-Phorbol; 17673-25-5
CAS No.:
17673-25-5
Compound CID:
442070
Formula:
C20H28O6
Formula Weight:
364.4
Specification
λmax:
230 nm
Solubility in DMSO:
30 mg/mL
Solubility in DMF:
30 mg/mL
Solubility in Other Solvents:
PBS: 1 mg/mL
Storage:
Storage at -20°C.
Applications:
Phorbol serves as a reference compound for phorbol ester-related chemical studies and supports analytical characterization and investigations involving structurally related diterpenoid derivatives.
