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5β-Cholestane-3α,7α,12α,25-tetrol
Cat. No.:
OB0626WX-200
Appearance:
Solid
Purity:
≥95%
Size:
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Product Overview
Description:
5β-Cholestane-3α,7α,12α,25-tetrol is a key hydroxylated bile acid alcohol that functions as an endogenous signaling mediator, stimulating the specific activation of G protein-coupled bile acid receptor 1 (GPBAR1/TGR5) in human receptor-expressing HEK293 cells across a responsive concentration spectrum ranging from 0.1 to 10 µM.
Synonyms:
3α,7α,12α,25-Tetrahydroxycoprostane; 5beta-Cholestane-3alpha,7alpha,12alpha,25-tetrol; Cholestane-3,7,12,25-tetrol; 5 beta cholestane-3 alpha,7 alpha,12 alpha,25-tetrol; 3alpha,7alpha,12alpha,25-Tetrahydroxycoprostane; (3alpha,5beta,7alpha,12alpha)-Cholestane-3,7,12,25-tetrol; Cholestane-3,7,12,25-tetrol, (3alpha,5beta,7alpha,12alpha)-; 18866-87-0
CAS No.:
18866-87-0
Compound CID:
5284211
Formula:
C27H48O4
Formula Weight:
436.7
Specification
Solubility in DMSO:
≥10 mg/mL
Solubility in Ethanol:
≥10 mg/mL
Storage:
Storage at -20°C.
Applications:
5β-Cholestane-3α,7α,12α,25-tetrol functions as a polyhydroxylated sterol reference compound for investigating sterol oxidation pathways, bile acid biosynthetic intermediates, and mass spectrometry-based characterization of hydroxylated sterol metabolites.
