Products
Online Inquiry
306-O12B
Cat. No.:
OB0626WX-3917
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, IR, and HPLC.
Size:
Add to basket
Product Overview
Description:
306-O12B is an ionizable cationic lipidoid core designed to serve as a principal component within stimuli-responsive lipid nanoparticle formulations. This ionizable architecture facilitates the precise encapsulation of macromolecular transcripts, driving visceral liver accumulation and highly efficient CRISPR-mediated gene knockdown to simultaneously reduce circulating serum lipoproteins and metabolic lipids.
Synonyms:
Tetrakis(2-(octyldisulfaneyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(propane-3,1-diyl))bis(azanetriyl))tetrapropionate; 16-Oxa-19,20-dithia-4,8,12-triazaoctacosanoic acid, 8-methyl-4,12-bis[3-[2-(octyldithio)ethoxy]-3-oxopropyl]-15-oxo-, 2-(octyldithio)ethyl ester; 2566523-06-4
CAS No.:
2566523-06-4
Compound CID:
155374947
Formula:
C59H115N3O8S8
Formula Weight:
1251.1
Specification
Solubility in Ethanol:
10 mg/mL
Storage:
Storage at -20°C.
Applications:
306-O12B serves as an experimental ionizable lipid for lipid nanoparticle development and nucleic acid delivery studies. It supports formulation screening, optimization of lipid composition, and investigation of physicochemical properties that influence nanoparticle performance and intracellular delivery.