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11R(12S)-EET
Cat. No.:
OB0626WX-297
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by HPLC.
Size:
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Product Overview
Description:
11R(12S)-EET is an endogenous oxylipin signaling mediator selectively biotransformed from arachidonic acid by the cytochrome P450 monooxygenase isoforms CYP2C23 and CYP2C24 preferentially over CYP2B2, and by CYP2C8 over CYP2C9.
Synonyms:
10-[(2R,3S)-3-(2Z)-2-octen-1-yl-2-oxiranyl]-5Z,8Z-decadienoic acid; 11R(12S)-EpETrE; 11R(12S)-Epoxy-all-cis-5,8,14-Eicosatrienoic Acid; 11R(12S)-Epoxyeicosatrienoic Acid; 11R(12S)-Epoxy-5(Z),8(Z),14(Z)-ETrE; FA 20:4;O; 11R,12S-EpETrE; 11R,12S-EET; 11R,12S-epoxy-5Z,8Z,14Z-eicosatrienoic acid; (11R,12S)-EET; 87173-81-7; (11R,12S)-EpETrE; 11(R),12(S)-EpETrE; 11(R),12(S)-EET
CAS No.:
123931-38-4
Compound CID:
6440793
Formula:
C20H32O3
Formula Weight:
320.5
Specification
Solubility in Ethanol:
0.1-1 mg/mL
Solubility in Other Solvents:
Acetonitrile: 1-10 mg/mL
Storage:
Storage at -20°C.
Applications:
11R(12S)-EET serves as a stereospecifically configured mid-chain epoxy-fatty acid model for profiling ionic channel activation kinetics, evaluating competitive enzymatic breakdown networks, and analyzing downstream lipophilic signaling flux.
