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Aflatoxin B1
Cat. No.:
OB0626WX-2676
Appearance:
Crystalline solid
Purity:
≥98%
Identity:
Confirmed by HPLC.
Size:
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Product Overview
Description:
Aflatoxin B1 is a potent, genotoxic mycotoxin produced by Aspergillus species that undergoes metabolic activation to form highly reactive DNA adducts within hepatic microsomal environments. This lipophilic carcinogen selectively drives specific guanine-to-thymine transversions at codon 29 of the p53 tumor suppressor gene network, disrupting normal cell cycle checkpoints and inducing robust hepatocellular carcinoma formation.
Synonyms:
2,3,6aR,9aS-tetrahydro-4-methoxy-1H,11H-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione; AFB1; NSC 529592; Aflatoxin B(1); 1162-65-8
CAS No.:
1162-65-8
Compound CID:
186907
Formula:
C17H12O6
Formula Weight:
312.3
Specification
λmax:
223 nm; 265 nm; 360 nm
Solubility in DMSO:
12 mg/mL
Solubility in DMF:
20 mg/mL
Solubility in Other Solvents:
DMF:PBS mixture: 0.5 mg/mL
Storage:
Storage at -20°C.
Applications:
Aflatoxin B1 is utilized as a reference compound for analytical detection and characterization of fungal-derived secondary metabolites. It supports mycotoxin profiling, chemical analysis, and studies of molecular interactions associated with aflatoxin-related biochemical research.
