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YK-009
Cat. No.:
OB0626WX-3858
Appearance:
Liquid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
YK-009 is a pH-responsive ionizable cationic lipid possessing a calculated pKa of 6.512, tailored for the architectural design of specialized lipid nanoparticle assemblies. This molecular platform optimizes oligonucleotide packaging and endosomal release mechanisms, supporting the protective delivery of viral variant transcripts to trigger robust antigen-specific humoral immune responses and elevated serum immunoglobulin production.
Synonyms:
6-[4-(decyloxy)-4-oxobutylamino]-hexanoic acid, 2-octyldecyl ester; 2-Octyldecyl 6-((4-(decyloxy)-4-oxobutyl)(2-hydroxyethyl)amino)hexanoate; YK009; 2761458-86-8
CAS No.:
2761458-86-8
Compound CID:
167713655
Formula:
C40H79NO5
Formula Weight:
654.1
Specification
Solubility in Ethanol:
5 mg/mL
Storage:
Storage at -20°C.
Applications:
YK-009 serves as a research ionizable lipid for lipid nanoparticle formulation and delivery optimization. It supports comparative evaluation of lipid structures, formulation development, physicochemical characterization, and studies of nucleic acid transport.