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Vacquinol-1
Cat. No.:
0225LY-1073
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
Vacquinol-1 selectively and rapidly triggers the death of glioma cells by acting as an MKK4 activator.
Synonym:
Vacquinol 1; 5428-80-8; NSC13316; (2-(4-chlorophenyl)quinolin-4-yl)(piperidin-2-yl)methanol; [2-(4-chlorophenyl)quinolin-4-yl]-piperidin-2-ylmethanol; [2-(4-chlorophenyl)quinolin-4-yl]-(2-piperidyl)methanol; (2-(4-chlorophenyl)-4-quinolinyl)(2-piperidinyl)methanol; (2-(4-chlorophenyl)quinolin-4-yl)-piperidin-2-ylmethanol
CAS No.:
5428-80-8
Compound CID:
224644
Formula:
C21H21ClN2
Formula Weight:
352.86
Specification
Relative Density:
1.244 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Vacquinol-1 can be used in neuro-oncology to investigate the induction of catastrophic vacuolization and death in glioblastoma cells.
Library Information
Target:
MKK4
Receptor:
MAP2K4
Pathways:
MAPK signaling; JNK cascade; Metabolism
Plate Number:
AOCL-14
Plate Location:
g8
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
70 mg/mL; 198.38 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
