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Trifolirhizin
Cat. No.:
OB0225WX-1907
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR.
Size:
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Product Overview
Description:
Trifolirhizin is a pterocarpan glycoside that suppresses tyrosinase-dependent melanin synthesis and induces relaxation of pre-contracted airway smooth muscle (ASM) through a mechanism independent of beta-2 adrenoceptors.
Synonym:
6807-83-6; MFCD00238700; (-)-maackiain-3-O-glucoside; (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(1R,12R)-5,7,11,19-tetraoxapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13(18),14,16-hexaen-16-yl]oxy]oxane-3,4,5-triol; trifolrhizin; (-)-Maackiain 3-O-glucoside; Sophojaponicin B2; (2S,3R,4S,5S,6R)-2-(((6aR,12aR)-6a,12a-Dihydro-6H-[1,3]dioxolo[4',5':5,6]benzofuro[3,2-c]chromen-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
CAS No.:
6807-83-6
Compound CID:
442827
Formula:
C22H22O10
Formula Weight:
446.4
Specification
Targets&IC50:
Tyrosinase: 506 μM (IC50)
Relative Density:
1.59 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Trifolirhizin is employed in pharmacological research as a flavonoid glycoside to investigate its potential in modulating immune responses and suppressing the production of pro-inflammatory cytokines.
Library Information
Target:
Tyrosinase; TNF
Receptor:
TNF-α; Tyrosinase
Pathways:
Apoptosis; Proteases/Proteasome
Plate Number:
AOCL-25
Plate Location:
d9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
81 mg/mL; 181.5 mM
