Products
Online Inquiry
Tafluprost-d4
Cat. No.:
OB0626WX-2453
Appearance:
Liquid
Purity:
≥99% (deuterated forms, d1–d4)
Identity:
Confirmed by IR, TLC, and HPLC.
Size:
Add to basket
Product Overview
Description:
Tafluprost-d4 is a deuterium-labeled internal standard intended for the precise mass spectrometric quantification of tafluprost. The corresponding unlabeled compound is a fluorinated prostaglandin F2α derivative structured as a lipophilic prodrug, which undergoes rapid ester cleavage to yield a potent FP receptor agonist capable of modifying pupillary mechanics and reducing intraocular pressure within normotensive ocular models.
Labeling:
Stable isotope-labeled
Synonyms:
(5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid-d4, 1-methylethyl ester; AFP-168-d4
Formula:
C25H30D4F2O5
Formula Weight:
456.6
Specification
Solubility in DMSO:
30 mg/mL
Solubility in Ethanol:
30 mg/mL
Solubility in DMF:
30 mg/mL
Storage:
Storage at -20°C.
Applications:
Tafluprost-d4 serves as a stable isotope-labeled internal standard for quantitative analysis of tafluprost and related metabolites. It supports isotope dilution LC-MS/MS analysis, analytical calibration, signal normalization, and pharmacokinetic and metabolic profiling in preclinical research.
