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SKLB-163
Cat. No.:
0225LY-1059
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
SKLB-163 exerts its biological effects by activating caspase-3 and JNK-1 signaling while simultaneously downregulating RhoGDI and decreasing the phosphorylation levels of p44/42 MAPK and Akt.
Synonym:
SKLB163; 1255099-06-9; N-Benzyl-2-((6-(2-chloroacetamido)benzo[d]thiazol-2-yl)thio)acetamide; 2-[[6-[(2-Chloroacetyl)amino]-2-benzothiazolyl]thio]-N-(phenylmethyl)-acetamide
CAS No.:
1255099-06-9
Compound CID:
51003475
Formula:
C18H16ClN3O2S2
Formula Weight:
405.92
Specification
Relative Density:
1.43 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
SKLB-163 can be used in oncology research to evaluate the inhibition of JNK signaling in colorectal cancer models.
Library Information
Target:
MAPK; Caspase; Rho; Akt; JNK
Receptor:
Akt; Caspase-3; JNK1; p44/42 MAPK; RhoGDI
Pathways:
MAPK; Apoptosis; Proteases/Proteasome; Cell cycle/Checkpoint; Cytoskeletal signaling; PI3K/Akt/mTOR signaling
Plate Number:
AOCL-14
Plate Location:
f4
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
247.5 mg/mL; 609.73 mM
