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SC-236
Cat. No.:
0225LY-0820
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, and LC-MS.
Size:
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Product Overview
Description:
SC-236 is an orally active and selective COX-2 inhibitor, showing a high preference for COX-2 (IC50: 0.005 uM) over COX-1 (IC50: 17.8 uM).
Synonym:
Sc 236; 170569-86-5; 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide; SC-58236; SC 236; SC236; 4-[5-(4-Chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; SC 58236; 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide; 9HGW1H8S2M; CHEMBL282093
CAS No.:
170569-86-5
Compound CID:
9865808
Formula:
C16H11ClF3N3O2S
Formula Weight:
401.79
Specification
Targets&IC50:
COX-1: 17.8 μM; COX-2: 0.005 μM
Relative Density:
1.54 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
SC-236 can be used in inflammation research to study the selective inhibition of the COX-2 enzyme.
Library Information
Target:
COX; PPAR
Receptor:
COX-2; PPAR
Pathways:
Immunology/Inflammation; Apoptosis; Metabolism; DNA damage/DNA repair; Neuronal signaling
Plate Number:
AOCL-11
Plate Location:
e9
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
22.5 mg/mL; 56 mM
