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SB 202190
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Cat. No.:
OB0125LY-099
Size:
25 mg; 50 mg; 100 mg; 200 mg
CAS No.:
152121-30-7
Compound CID:
5169
Specification
Description:
SB 202190 is a selective p38 MAPK inhibitor that regulates signaling associated with cellular stress, inflammation, and cell growth by interfering with the p38 MAPK pathway.
Formula Weight:
331.34
Stability:
3 years in powder form.
Applications:
SB 202190 can be used as a research tool to explore the role of p38 MAPK activation in pathological processes.
Storage:
Storage at -20°C.
Formula:
C20H14FN3O
Appearance:
Solid
Purity:
99.8%
Identity:
Confirmed by NMR and HPLC.
Targets&IC50:
p38α: 50 nM (cell free); p38β: 100 nM (cell free)
Relative Density:
1.311 g/cm3
Library Information
Plate Number:
AOCL-7
Plate Location:
c2
Empty Location:
a1-h1; a12-h12
Formulation:
10mM DMSO
Container:
96-well plate
Pathways:
Autophagy; Apoptosis; MAPK
Targets:
Autophagy; Apoptosis; p38 MAPK
Receptors:
Apoptosis; Autophagy; p38 MAPK; p38α; p38β
DMSO Max Solubility (mg/mL):
50 mg/mL
DMSO Max Solubility (mM):
150.9 mM
Saline Max Solubility (mg/mL):
3.31 mg/mL
Saline Max Solubility (mM):
9.99 mM
ALogP:
4.211
HBA_Count:
2
HBD_Count:
2
Rotatable Bond:
3