Saroglitazar magnesium

Cat. No.: OB0225WX-2216

Appearance: Solid

Purity: ≥98%

Identity: Confirmed by NMR, and LC-MS.

Size:

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Product Overview

Description: Saroglitazar magnesium is a dual peroxisome proliferator-activated receptor (PPAR) agonist possessing potent activation potency for PPAR-alpha (EC50: 0.65 pM) and moderate activity toward PPAR-gamma (EC50: 3 nM).

Synonym: 1639792-20-3; (2S)-2-Ethoxy-3-(4-(2-(2-methyl-5-(4-(methylsulfanyl)phenyl)-1H-pyrrol-1-yl(ethoxy)phenyl)propanoic acid, magnesium salt (2:1); Magnesium;(2S)-2-ethoxy-3-[4-[2-[2-methyl-5-(4-methylsulfanylphenyl)pyrrol-1-yl]ethoxy]phenyl]propanoate; Magnesium, bis((alphaS)-alpha-(ethoxy-kappaO)-4-(2-(2-methyl-5-(4-(methylthio)phenyl)-1H-pyrrol-1-yl)ethoxy)benzenepropanoato-kappaO)-, (T-4)-; (2S)-2-ethoxy-3-(4-(2-(2-methyl-5-(4-(methylsulfanyl)phenyl)-1H-pyrrol-1-yl(ethoxy)phenyl)propanoic acid magnesium salt (2:1); Alpha-ethoxy-4-(2-(2-methyl-5-(4-methylthio)phenyl))-1H-pyrrol-1-yl)ethoxy))benzenepropanoic acid magnesium salt

CAS No.: 1639792-20-3

Compound CID: 121000421

Formula: C₅₀H₅₆MgN₂O₈S₂

Formula Weight: 901.43

Specification

Targets&IC50: PPARγ: 3 nM (EC50; HepG2 cell); PPARα: 0.65 pM (EC50; HepG2 cell)

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Saroglitazar magnesium is utilized in metabolic and cardiovascular research as a dual PPAR alpha/gamma agonist to investigate the improvement of insulin sensitivity and the management of diabetic dyslipidemia.