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Remisporine B
Cat. No.:
OB0626WX-823
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by HPLC.
Size:
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Product Overview
Description:
Remisporine B is a macrocyclic polyketide derivative obtained as a specialized structural modification of remisporine A within the Penicillium genus, demonstrating targeted immunosuppressive activity that directly restricts adaptive immune cell activation by blocking lipopolysaccharide- or concanavalin A-induced proliferation of isolated mouse splenic lymphocytes.
Synonyms:
(5bS,7S,7aR,7bR,14bS)-7,7a,7b,8,14,14b-hexahydro-4,7,13-trihydroxy-2,11-dimethyl-5,14-dioxo-furo[2′,3′,4′:3,4]indeno[1,2-b:6,7-b′]bis[1]benzopyran-5b,7(5H)-dicarboxylic acid, dimethyl ester; 571194-06-4; Dimethyl (1S,12S,14S,15R,27R)-8,14,23-trihydroxy-6,21-dimethyl-10,25-dioxo-3,13,18-trioxaheptacyclo[13.11.1.02,11.04,9.012,27.017,26.019,24]heptacosa-2(11),4,6,8,17(26),19,21,23-octaene-12,14-dicarboxylate
CAS No.:
571194-06-4
Compound CID:
155859171
Formula:
C30H24O12
Formula Weight:
576.5
Specification
Source:
Remispora maritima
Solubility in DMSO:
Soluble
Solubility in Other Solvents:
Soluble in methanol.
Storage:
Storage at -20°C.
Applications:
Remisporine B operates as a structurally complex cyclopentenone dimer reference matrix for evaluating localized bilayer lipid-protein binding domains, profiling target enzyme conversion kinetics, and quantifying the influence of rigid polycyclic systems on structural lipid configurations.
