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PLC thio-PIP2, sodium salt
Cat. No.:
OB0626WX-3024
Appearance:
Lyophilized powder
Purity:
≥98%
Identity:
Confirmed by NMR.
Size:
Add to basket
Product Overview
Description:
PLC thio-PIP2 is a synthetic, sulfur-substituted substrate analogue of natural phosphatidylinositol 4,5-bisphosphate configured with a thioester linkage at the sn-3 position of its glycerol backbone. Designed as a targeted kinetic tool, phosphoinositide-specific phospholipase C cleavage of this substrate yields a free thiol product that undergoes rapid, stoichiometric conjugation with chromogenic reagents to monitor signal transduction activity.
Synonyms:
3-(3-(1,2-dihydroxy-1,2-dihexanoyl)thiopropane)inositol-4,5-diphosphate, trisodium salt
Formula:
C21H38O18P3S • 3Na
Formula Weight:
772.5
Specification
Storage:
Storage at -20°C.
Applications:
PLC thio-PIP2, sodium salt provides a modified phosphoinositide substrate for biochemical research involving phosphatidylinositol signaling-related enzymatic reactions. It supports lipid enzyme studies, substrate characterization, and analysis of phosphoinositide transformation processes.
