Products
Online Inquiry
Pazopanib hydrochloride
Inquiry
Cat. No.:
OB0125LY-098
Size:
10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg
CAS No.:
635702-64-6
Compound CID:
11525740
Specification
Description:
Pazopanib hydrochloride is a small molecule multi-targeted tyrosine kinase inhibitor that inhibits multiple tyrosine kinases and affects tumor growth and angiogenesis.
Formula Weight:
473.98
Stability:
3 years in powder form.
Applications:
Pazopanib hydrochloride effectively controls tumor progression by inhibiting angiogenic and cell signaling pathways associated with tumor growth.
Storage:
Storage at -20°C.
Formula:
C21H23N7O2S·HCl
Appearance:
Solid
Purity:
99.7%
Identity:
Confirmed by NMR and HPLC.
Targets&IC50:
c-Kit: 140 nM; PDGFR: 84 nM; VEGFR2: 30 nM; VEGFR3: 47 nM; FGFR: 74 nM; VEGFR1: 10 nM; c-Fms: 146 nM
Library Information
Plate Number:
AOCL-7
Plate Location:
b5
Empty Location:
a1-h1; a12-h12
Formulation:
10mM DMSO
Container:
96-well plate
Pathways:
Autophagy; Angiogenesis; Tyrosine kinase/adaptors
Targets:
PDGFR; c-Kit; FGFR; c-Fms; VEGFR; Autophagy
Receptors:
Autophagy; c-Fms; c-Kit; FGFR; PDGFR; VEGFR; VEGFR1; VEGFR2; VEGFR3
DMSO Max Solubility (mg/mL):
7.5 mg/mL
DMSO Max Solubility (mM):
15.82 mM
Water Max Solubility (mg/mL):
1 mg/mL
Ethanol Max Solubility (mg/mL):
1 mg/mL
ALogP:
4.123
HBA_Count:
5
HBD_Count:
2
Rotatable Bond:
5