Pazopanib hydrochloride

Cat. No.: OB0125LY-098

Appearance: Solid

Purity: 99.7%

Identity: Confirmed by NMR and HPLC.

Size:

INQUIRY Datasheet MSDS

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Product Overview

Description: Pazopanib hydrochloride is a small molecule multi-targeted tyrosine kinase inhibitor that inhibits multiple tyrosine kinases and affects tumor growth and angiogenesis.

Synonym: 635702-64-6; Pazopanib HCl; Votrient HCl; Armala; Pazopanib hydrochloride; 5-[[4-[ (2,3-Dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride; 5-( (4-( (2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride; 5-({4-[ (2,3-Dimethyl-2H-indazol-6-yl) (methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzene-1-sulfonamide hydrochloride; 5-( (4-( (2,3-Dimethyl-2H-indazol-6-yl) (methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride; 5-({4-[ (2,3-Dimethyl-2H-indazol-6-yl) (methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzenesulfonamide Hydrochloride; 5-[[4-[ (2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide hydrochloride

CAS No.: 635702-64-6

Compound CID: 11525740

Formula: C₂₁H₂₃N₇O₂S·HCl

Formula Weight: 473.98

Specification

Targets & IC50: c-Kit: 140 nM; PDGFR: 84 nM; VEGFR2: 30 nM; VEGFR3: 47 nM; FGFR: 74 nM; VEGFR1: 10 nM; c-Fms: 146 nM

Stability: 3 years in powder form.

Storage: Storage at -20°C.

Applications: Pazopanib hydrochloride effectively controls tumor progression by inhibiting angiogenic and cell signaling pathways associated with tumor growth.