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Pamapimod
Cat. No.:
OB0225LY-0456
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and HPLC.
Size:
Product Overview
Description:
Pamapimod is a selective p38 MAPK inhibitor that is primarily used in the study of inflammation and stress response.
Synonym:
R1503; Ro4402257; 449811-01-2; RO 4402257; 6-(2,4-Difluorophenoxy)-2-(1,5-dihydroxypentan-3-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one; 6-(2,4-Difluorophenoxy)-2-[[3-hydroxy-1-(2-hydroxyethyl)propyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one; Pyrido(2,3-d)pyrimidin-7(8H)-one, 6-(2,4-difluorophenoxy)-2-((3-hydroxy-1-(2-hydroxyethyl)propyl)amino)-8-methyl-
CAS No.:
449811-01-2
Compound CID:
16220188
Formula:
C19H20F2N4O4
Formula Weight:
406.38
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
Pamapimod can be used in the study of chronic inflammation models or play an important role in the drug development process.
Library Information
Targets:
Kinases
Receptors:
p38α; p38β
Pathways:
Autophagy; MAPK
Plate Number:
AOCL-6
Plate Location:
h3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
45 mg/mL; 110.73 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
Ethanol Max Solubility:
27 mg/mL; 66.4 mM
ALogP:
1.298
HBA_Count:
4
HBD_Count:
3
Rotatable Bond:
8
