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Palmitic acid-13C16
Cat. No.:
OB0626WX-19
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR and HPLC.
Size:
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Product Overview
Description:
Palmitic acid-13C16 is a fully carbon-labeled stable isotope optimized for use as an analytical internal standard for the quantification of native palmitic acid by GC- or LC-MS. As a ubiquitous 16-carbon saturated fatty acid accounting for 10-20% of human dietary fat intake, palmitic acid constitutes approximately 25% of human total plasma lipids and 65% of total saturated fatty acids, facilitating protein anchoring to the lipid bilayer and intracellular protein trafficking via protein acylation while regulating G protein-coupled receptor functions. Extensive cellular and in vivo data demonstrate that 200 µM of palmitic acid promotes migration and increases NF-kappaB p65 levels, MMP-9 activity, and ROS production in AsPC-1 pancreatic cancer cells, elevates COX-2 expression in RAW 264.7 cells, and enhances LPS-induced IL-1beta levels and caspase-1 activity in isolated mouse peritoneal macrophages; furthermore, a dietary regimen of 2.2% w/w palmitic acid for 12 weeks increases mouse hippocampal BACE1 activity and amyloid beta (1-42) levels, induces systolic contractile dysfunction in isolated mouse hearts, and shows marked elevation in the red blood cells of metabolic syndrome patients and the plasma of type 2 diabetes cohorts.
Labeling:
Stable isotope-labeled
Synonyms:
Hexadecanoic-1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16-13C16 acid; C16:0-13C16; Cetylic Acid-13C16; FA 16:0-13C16; 56599-85-0; (1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16-13C16)Hexadecanoic acid; Hexadecanoic acid-13C16; Palmitic acid-(1)(3)C16; (~13~C_16_)Hexadecanoic acid
CAS No.:
56599-85-0
Compound CID:
16217538
Formula:
13C16H32O2
Formula Weight:
272.3
Specification
Solubility in Ethanol:
0.1-1 mg/mL
Solubility in Other Solvents:
Chloroform: 0.1-1 mg/mL
Storage:
Storage at -20°C.
Applications:
Palmitic acid-13C16 serves as a carbon-labeled fatty acid tracer and analytical reference compound for studying saturated fatty acid metabolism and lipid biosynthetic processes. It supports isotope tracing experiments, quantitative lipidomics, and characterization of fatty acid incorporation and transformation pathways.