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N-Arachidonyl maleimide
Cat. No.:
OB0626WX-2976
Appearance:
Liquid
Purity:
≥98%
Identity:
Confirmed by IR, TLC, and HPLC.
Size:
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Product Overview
Description:
N-Arachidonyl maleimide is a highly potent, lipophilic irreversible inhibitor engineered to target monoacylglycerol lipase activity. Featuring a reactive sulfated maleimide headgroup conjugated to an arachidonoyl chain, the molecule forms covalent bonds with critical cysteine residues within the enzyme's substrate-binding pocket, halting the termination cascade of endocannabinoid signaling.
Synonyms:
NAM; N-Arachidonylmaleimide; Eicosa-5Z,8Z,11Z,14Z-tetraenyl-1-pyrrole-2,5-dione; 876305-42-9; 1-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl]pyrrole-2,5-dione
CAS No.:
876305-42-9
Compound CID:
25021164
Formula:
C24H35NO2
Formula Weight:
369.5
Specification
Solubility in DMSO:
30 mg/mL
Solubility in Ethanol:
50 mg/mL
Solubility in DMF:
30 mg/mL
Storage:
Storage at -80°C.
Applications:
N-Arachidonyl maleimide provides a chemical biology tool for investigating arachidonate-derived lipid interactions and reactive lipid chemistry. It can be utilized in lipid modification studies, molecular interaction analysis, and characterization of arachidonic acid-derived molecular probes.
