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Lyso-Monosialoganglioside GM1, ammonium salt
Cat. No.:
OB0626WX-1946
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by TLC.
Size:
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Product Overview
Description:
Lyso-monosialoganglioside GM1 is a deacylated, amphiphilic form of ganglioside GM1 lacking a traditional hydrophobic fatty acyl group. This active lipid serves as a crucial pathological marker that accumulates within central nervous tissues during inherited β-galactosidase deficiencies and functions as a signaling disruptor that impairs integrin clustering, prevents ganglioside microdomain assembly, and restricts neurite outgrowth.
Synonyms:
(2S,3R,4E)-2-amino-3-hydroxy-4-octadecenyl O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside, monoammonium salt; Lysoganglioside GM1; Lyso-GM1; lyso-Monosialoganglioside GM1
Formula:
C55H96N3O30 • NH4
Formula Weight:
1297.4
Specification
Storage:
Storage at -20°C.
Applications:
Lyso-Monosialoganglioside GM1, ammonium salt functions as a deacylated ganglioside derivative standard that serves as an analytical reference tool for mass spectrometry method development, supporting structural identification metrics and the investigation of lysosphingolipid-associated metabolic pathways.
