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LY-2584702 tosylate salt
Cat. No.:
0225LY-0807
Appearance:
Solid
Purity:
≥98%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
LY-2584702 tosylate salt is an ATP-competitive and selective p70S6K inhibitor currently undergoing clinical evaluation for oncological treatments.
Synonym:
1082949-68-5; LY2584702 tosylate; 4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine 4-methylbenzenesulfonate; 4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methylimidazol-2-yl]piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine;4-methylbenzenesulfonic acid; 4-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pyrazolo[3,4-d]pyrimidine p-toluenesulfonate
CAS No.:
1082949-68-5
Compound CID:
46205871
Formula:
C28H27F4N7O3S
Formula Weight:
617.62
Specification
Targets&IC50:
p70 S6K: 4 nM
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
LY-2584702 tosylate salt can be used in molecular oncology to examine the targeted inhibition of p70S6K in tumor models.
Library Information
Target:
p70 S6K
Receptor:
S6K family
Pathways:
PI3K/Akt/mTOR signaling
Plate Number:
AOCL-11
Plate Location:
d6
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
12 mg/mL; 19.43 mM
Ethanol Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
