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Lipid catechol
Cat. No.:
OB0626WX-3852
Appearance:
Solid
Purity:
≥95%
Identity:
Confirmed by NMR, TLC, and HPLC.
Size:
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Product Overview
Description:
Lipid catechol is a multi-functional amphiphilic lipid incorporating an alpha-aminophosphonate center, dual 14-carbon acyl chains, and a reactive catechol headgroup designed to form reversible covalent bonds with boronic acid derivatives. This chemical pairing yields stable prodrug nanoassemblies that exploit localized microenvironments to disrupt established bacterial biofilms, eradicate persistent pathogens, and suppress mammary tumor volume while improving overall survival profiles.
Synonyms:
ditetradecyl (((2-(diethylamino)ethyl)amino)(3,4-dihydroxyphenyl)methyl)phosphonate; 2930813-52-6
CAS No.:
2930813-52-6
Compound CID:
171042958
Formula:
C41H79N2O5P
Formula Weight:
711.1
Specification
Solubility in DMSO:
1 mg/mL
Solubility in Ethanol:
1 mg/mL
Storage:
Storage at -20°C.
Applications:
Lipid catechol serves as a synthetic ionizable lipid for investigating lipid nanoparticle formulation and nucleic acid delivery. It supports formulation optimization, structure–activity relationship studies, nanoparticle physicochemical characterization, and evaluation of lipid-mediated intracellular delivery mechanisms.
