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α-hydroxy Farnesyl phosphonic acid
Cat. No.:
OB0626WX-2953
Appearance:
Crystalline solid
Purity:
≥98%
Identity:
Confirmed by IR.
Size:
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Product Overview
Description:
α-hydroxy Farnesyl phosphonic acid is a hydrolytically stable, nonhydrolyzable phosphonate analogue of farnesyl pyrophosphate. This molecule functions as a competitive enzymatic inhibitor, targeting lipid modification machinery to disrupt farnesyl transferase activity and block the post-translational lipid processing of Ras signaling proteins within transformed cellular models.
Synonyms:
(±)-1-hydroxy-3,7,11-trimethyl-2E,6E,10-dodecatriene-1-phosphonic acid; Hydroxyfarnesyl Phosphate; (alpha-hydroxyfarnesyl)phosphonic acid; alpha-HOF-phosphonic acid; alpha-hydroxy farnesylphosphonic acid; alpha-hydroxyfarnesylphosphonic acid; 148796-53-6
CAS No.:
148796-53-6
Compound CID:
46937103
Formula:
C15H27O4P
Formula Weight:
302.4
Specification
Solubility in Ethanol:
>25 mg/mL
Solubility in Other Solvents:
PBS: <25 µg/mL
Storage:
Storage at -20°C.
Applications:
α-hydroxy Farnesyl phosphonic acid serves as a lipid-related research compound for investigating prenyl-related biochemical processes, structural characterization, and analysis of modified isoprenoid derivatives. It supports analytical studies and chemical biology research involving lipid-like molecules.
