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HhAntag
Cat. No.:
0225LY-0548
Purity:
≥95%
Identity:
Confirmed by NMR.
Size:
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Product Overview
Description:
HhAntag is a small molecule designed to inhibit GLI1-mediated transcription, which is a critical downstream component of the Hedgehog (Hh) pathway, thereby providing anti-tumor activity.
Synonym:
496794-70-8; N-(4-Chloro-3-(5-(dimethylamino)-1H-benzo[d]imidazol-2-yl)phenyl)-3,5-dimethoxybenzamide; GLI1-mediated transcription inhibitor; N-[4-Chloro-3-[6-(dimethylamino)-1H-benzimidazol-2-yl]phenyl]-3,5-dimethoxybenzamide
CAS No.:
496794-70-8
Compound CID:
9911630
Formula:
C24H23ClN4O3
Formula Weight:
450.92
Specification
Relative Density:
1.337 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
HhAntag can be used in preclinical tumor models to explore the impact of systemically blocking the Hedgehog signal.
Library Information
Target:
GLI1
Receptor:
GLI1
Pathways:
Hedgehog signaling; Stem cell regulation; Developmental biology
Plate Number:
AOCL-8
Plate Location:
b2
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
55 mg/mL; 121.97 mM
