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H-89 dihydrochloride
Cat. No.:
OB0225LY-0475
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR and LC-MS.
Size:
Product Overview
Description:
H-89 dihydrochloride is a selective PKA inhibitor commonly used to study cell signaling.
Synonym:
Protein kinase inhibitor H-89 dihydrochloride; H 89 2HCl; 5-Isoquinolinesulfonamide; 130964-39-5; N-(2-((3-(4-Bromophenyl)allyl)amino)ethyl)isoquinoline-5-sulfonamide dihydrochloride; N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide; dihydrochloride
CAS No.:
130964-39-5
Compound CID:
5702541
Formula:
C20H20BrN3O2S·2HCl
Formula Weight:
519.28
Specification
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
H-89 dihydrochloride can be used in the study of cell signaling regulation or play an important role in the study of metabolic regulation.
Library Information
Targets:
Kinases
Receptors:
PKA; S6K1
Pathways:
MAPK; Tyrosine kinase/adaptors; PI3K/Akt/mTOR signaling; Autophagy
Plate Number:
AOCL-7
Plate Location:
b3
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10 mM DMSO
DMSO Max Solubility:
60 mg/mL; 115.54 mM
Water Max Solubility:
<1 mg/mL (insoluble or slightly soluble)
ALogP:
3.665
HBA_Count:
3
HBD_Count:
2
Rotatable Bond:
8





