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Glycodeoxycholic acid (hydrate)
Cat. No.:
OB0626WX-2232
Appearance:
Crystalline solid
Purity:
≥95%
Identity:
Confirmed by IR and TLC.
Size:
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Product Overview
Description:
Glycodeoxycholic acid is a glycine-conjugated secondary bile acid that modulates vascular and metabolic homeostatic pathways. This amphiphilic sterol derivative influences smooth muscle myogenic tone, regulates hepatic cytochrome P450 transcription, and exhibits marked systemic concentration increases in acute hepatic injury and respiratory pathologies.
Synonyms:
N-[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]-glycine, monohydrate; GDCA; 1079043-81-4; Glycodeoxycholic acid free acid; Glycodeoxycholic acid monohydrate; Glycodeoxycholic acid (monohydrate); 2-[[(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid;hydrate; 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)acetic acid hydrate
CAS No.:
1079043-81-4
Compound CID:
16219427
Formula:
C26H43NO5 • H2O
Formula Weight:
467.6
Specification
Solubility in DMSO:
10 mg/mL
Solubility in Ethanol:
1 mg/mL
Solubility in DMF:
10 mg/mL
Solubility in Other Solvents:
DMSO:PBS mixture: 0.2 mg/mL
Storage:
Storage at -20°C.
Applications:
Glycodeoxycholic acid (hydrate) serves as a reference compound for bile acid metabolism research and targeted metabolomic analysis. It supports LC-MS/MS-based bile acid profiling, investigations of bile acid biotransformation, enterohepatic circulation, and characterization of glycine-conjugated bile acid metabolism.
