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Ganglioside GM3 from bovine brain, sodium salt
Cat. No.:
OB0626WX-2563
Appearance:
Lyophilized solid
Purity:
≥98%
Identity:
Confirmed by NMR and TLC.
Size:
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Product Overview
Description:
Ganglioside GM3 is a foundational monosialoganglioside structure possessing a predominantly C18:0 fatty acyl chain linked to a natural sphingoid backbone, known for its extensive regulatory control over cellular proliferation, adhesion, and apoptotic pathways. This bioactive glycosphingolipid impairs vascular endothelial growth factor receptor 2 and Akt phosphorylation cascades to suppress angiogenic cell migration, while simultaneously orchestrating the dissociation of receptor complexes from membrane microdomains to modulate insulin signaling networks.
Synonyms:
Hematoside Sialosyllactosylceramide; G(M3) Ganglioside; Hematoside; Sialyllactosylceramide; Ganglioside GM3; II3NeuAcLacCer; Sialyl Lactosylceramide; 54827-14-4
CAS No.:
54827-14-4
Compound CID:
86583360
Formula:
C59H107N2O21 • Na (for tricosanoyl)
Formula Weight:
1203.5
Specification
Source:
Bovine brain
Storage:
Storage at -20°C.
Applications:
Ganglioside GM3 from bovine brain, sodium salt is utilized in studies of glycosphingolipid metabolism, membrane organization, and lipid composition analysis. It provides a reference standard for ganglioside identification, lipidomic profiling, and investigations of carbohydrate-containing lipid structures.
