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FB23
Cat. No.:
OB0225WX-2244
Appearance:
Solid
Purity:
≥99%
Identity:
Confirmed by NMR, HPLC, and LC-MS.
Size:
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Product Overview
Description:
FB23 is a small-molecule ligand that directly binds to FTO (mRNA N6-methyladenosine demethylase) and selectively suppresses its m6A demethylase enzymatic activity.
Synonym:
2243736-35-6; 2-((2,6-Dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)benzoic acid; 2-[[2,6-bis(chloranyl)-4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]amino]benzoic acid; 2-[2,6-dichloro-4-(3,5-dimethyl-1,2-oxazol-4-yl)anilino]benzoic acid; 2-{[2,6-dichloro-4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]amino}benzoic acid
CAS No.:
2243736-35-6
Compound CID:
138393314
Formula:
C18H14Cl2N2O3
Formula Weight:
377.22
Specification
Targets&IC50:
FTO: 60 nM (IC50)
Relative Density:
1.419 g/cm3
Stability:
3 years in powder form.
Storage:
Storage at -20°C.
Applications:
FB23 is employed in epigenetic and oncology research as a potent and selective inhibitor of the FTO demethylase to investigate the modulation of RNA methylation and its impact on the growth of leukemia cells.
Library Information
Target:
FTO
Receptor:
FTO
Pathways:
Others
Plate Number:
AOCL-29
Plate Location:
f10
Empty Location:
a1-h1; a12-h12
Container:
96-well plate
Formulation:
10mM DMSO
DMSO Max Solubility:
25 mg/mL; 66.27 mM
